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Interactions within the MHC contribute to the genetic architecture of celiac disease

Interaction analysis of GWAS can detect signal that would be ignored by single variant analysis, yet few robust interactions in humans have been detected. Recent work has highlighted interactions in the MHC region between known HLA risk haplotypes for various autoimmune diseases. To better understan...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Goudey, Benjamin, Abraham, Gad, Kikianty, Eder, Wang, Qiao, Rawlinson, Dave, Shi, Fan, Haviv, Izhak, Stern, Linda, Kowalczyk, Adam, Inouye, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345796/
https://ncbi.nlm.nih.gov/pubmed/28282431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172826
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