Depletion of cardiac catecholamine stores impairs cardiac norepinephrine re-uptake by downregulation of the norepinephrine transporter

In heart failure (HF), a disturbed cardiac norepinephrine (NE) homeostasis is characterized by depleted cardiac NE stores, impairment of the cardiac NE re-uptake by the neuronal norepinephrine transporter (NET) and enhanced cardiac NE net release. Reduced cardiac NE content appears to be caused by e...

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Pubblicato in:PLoS One
Autori principali: Kreusser, Michael M., Lehmann, Lorenz H., Haass, Markus, Buss, Sebastian J., Katus, Hugo A., Lossnitzer, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345760/
https://ncbi.nlm.nih.gov/pubmed/28282374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172070
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