Increasing efficiency of preclinical research by group sequential designs

Despite the potential benefits of sequential designs, studies evaluating treatments or experimental manipulations in preclinical experimental biomedicine almost exclusively use classical block designs. Our aim with this article is to bring the existing methodology of group sequential designs to the...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Neumann, Konrad, Grittner, Ulrike, Piper, Sophie K., Rex, Andre, Florez-Vargas, Oscar, Karystianis, George, Schneider, Alice, Wellwood, Ian, Siegerink, Bob, Ioannidis, John P. A., Kimmelman, Jonathan, Dirnagl, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Perspective
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345756/
https://ncbi.nlm.nih.gov/pubmed/28282371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001307
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