Repeated otilonium bromide administration prevents neurotransmitter changes in colon of rats underwent to wrap restraint stress

Otilonium bromide (OB) is a spasmolytic drug successfully used for the treatment of irritable bowel syndrome (IBS). Its efficacy has been attributed to the block of L‐ and T‐type Ca(2+) channels and muscarinic and tachykinin receptors in the smooth muscle. Furthermore, in healthy rats, repeated OB a...

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Pubblicato in:J Cell Mol Med
Autori principali: Traini, Chiara, Evangelista, Stefano, Girod, Vincent, Faussone‐Pellegrini, Maria Simonetta, Vannucchi, Maria Giuliana
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345670/
https://ncbi.nlm.nih.gov/pubmed/27866394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13016
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