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Morroniside, a secoiridoid glycoside from Cornus officinalis , attenuates neuropathic pain by activation of spinal glucagon‐like peptide‐1 receptors
BACKGROUND AND PURPOSE: Iridoid glycosides containing the double bond scaffold of cyclopentapyran are reversible and orthosteric agonists of glucagon‐like peptide‐1 (GLP‐1) receptors and exert anti‐nociceptive and neuroprotective actions. Morroniside, derived from the medicinal herb Cornus officinal...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345663/ https://ncbi.nlm.nih.gov/pubmed/28098360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13720 |
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