Identification of recurrent BRCA1 mutation and its clinical relevance in Chinese Triple‐negative breast cancer cohort

Triple‐negative breast cancer (TNBC) accounts for 15–20% of all newly diagnosed breast cancers, and is enriched for germline mutation of BRCA. In Asian patients diagnosed with breast cancer, 268 deleterious mutations of BRCA1 and 242 of BRCA2 have been identified so far, including a reported BRCA1 f...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Liu, Xiaoran, Li, Huiping, Shao, Bin, Wu, Jianmin, Kong, Weiyao, Song, Guohong, Jiang, Hanfang, Wang, Jing, Wan, Fengling
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345662/
https://ncbi.nlm.nih.gov/pubmed/28135048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1004
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