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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
Stimulation of cells with various peptide growth factors induces the production of phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) through activation of phosphatidylinositol 3-kinase. The action of this enzyme is reversed by that of the tumor suppressor PTEN. With the use of cells overexpressing N...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534546/ https://ncbi.nlm.nih.gov/pubmed/15534200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407396101 |
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