New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Cationic amphiphilic drugs (CADs) comprise a wide variety of different substance classes such as antidepressants, antipsychotics, and antiarrhythmics. It is well recognized that CADs accumulate in certain intracellular compartments leading to specific morphological changes of cells. So far, no adequ...

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Pubblicato in:Sci Rep
Autori principali: Vater, Magdalena, Möckl, Leonhard, Gormanns, Vanessa, Schultz Fademrecht, Carsten, Mallmann, Anna M., Ziegart-Sadowska, Karolina, Zaba, Monika, Frevert, Marie L., Bräuchle, Christoph, Holsboer, Florian, Rein, Theo, Schmidt, Ulrike, Kirmeier, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345070/
https://ncbi.nlm.nih.gov/pubmed/28281674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44277
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