New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Cationic amphiphilic drugs (CADs) comprise a wide variety of different substance classes such as antidepressants, antipsychotics, and antiarrhythmics. It is well recognized that CADs accumulate in certain intracellular compartments leading to specific morphological changes of cells. So far, no adequ...

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Udgivet i:Sci Rep
Main Authors: Vater, Magdalena, Möckl, Leonhard, Gormanns, Vanessa, Schultz Fademrecht, Carsten, Mallmann, Anna M., Ziegart-Sadowska, Karolina, Zaba, Monika, Frevert, Marie L., Bräuchle, Christoph, Holsboer, Florian, Rein, Theo, Schmidt, Ulrike, Kirmeier, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345070/
https://ncbi.nlm.nih.gov/pubmed/28281674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44277
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