Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Development of systems that reconstitute hallmark features of human pancreatic intraepithelial neoplasia (PanINs), the precursor to pancreatic ductal adenocarcinoma, could generate new strategies for early diagnosis and intervention. However, human cell-based PanIN models with defined mutations are...

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Publicado en:Nat Commun
Main Authors: Lee, Jonghyeob, Snyder, Emily R., Liu, Yinghua, Gu, Xueying, Wang, Jing, Flowers, Brittany M., Kim, Yoo Jung, Park, Sangbin, Szot, Gregory L., Hruban, Ralph H., Longacre, Teri A., Kim, Seung K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344977/
https://ncbi.nlm.nih.gov/pubmed/28272465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14686
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