Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus

The neurodevelopmental factor dysbindin is required for synapse function and GABA interneuron development. Dysbindin protein levels are reduced in the hippocampus of schizophrenia patients. Mouse dysbindin genetic defects and other mouse models of neurodevelopmental disorders share defective GABAerg...

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Bibliographic Details
Published in:Front Genet
Main Authors: Larimore, Jennifer, Zlatic, Stephanie A., Arnold, Miranda, Singleton, Kaela S., Cross, Rebecca, Rudolph, Hannah, Bruegge, Martha V., Sweetman, Andrea, Garza, Cecilia, Whisnant, Eli, Faundez, Victor
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344932/
https://ncbi.nlm.nih.gov/pubmed/28344592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00028
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