Suppression and Synthetic-Lethal Genetic Relationships of ΔgpsB Mutations Indicate That GpsB Mediates Protein Phosphorylation and Penicillin-Binding Protein Interactions in Streptococcus pneumoniae D39

GpsB regulatory protein and StkP protein kinase have been proposed as molecular switches that balance septal and peripheral (side-wall like) peptidoglycan (PG) synthesis in Streptococcus pneumoniae (pneumococcus); yet, mechanisms of this switching remain unknown. We report that ΔdivIVA mutations are...

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Publié dans:Mol Microbiol
Auteurs principaux: Rued, Britta E., Zheng, Jiaqi J., Mura, Andrea, Tsui, Ho-Ching T., Boersma, Michael J., Mazny, Jeffrey L., Corona, Federico, Perez, Amilcar J., Fadda, Daniela, Doubravová, Linda, Buriánková, Karolína, Branny, Pavel, Massidda, Orietta, Winkler, Malcolm E.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344783/
https://ncbi.nlm.nih.gov/pubmed/28010038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13613
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