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Baseline EDSS proportions in MS clinical trials affects the overall outcome and power: a cautionary note
BACKGROUND: In randomized clinical trials, when treatments do not work equally effectively across stratifications of participants, observed event rates may differ from those hypothesized leading to deviations in estimated power. OBJECTIVES: To investigate the effect of distributions of baseline EDSS...
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| Udgivet i: | Mult Scler |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344761/ https://ncbi.nlm.nih.gov/pubmed/27682227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458516670733 |
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