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Lethal Dysregulation of Energy Metabolism During Embryonic Vitamin E Deficiency

Vitamin E (α-tocopherol, VitE) was discovered in 1922 for its role in preventing embryonic mortality. We investigated the underlying mechanisms causing lethality using targeted metabolomics analyses of zebrafish VitE-deficient embryos over five days of development, which coincided with their increas...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: McDougall, Melissa, Choi, Jaewoo, Kim, Hye-Kyeong, Bobe, Gerd, Stevens, J. Frederik, Cadenas, Enrique, Tanguay, Robert, Traber, Maret G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344700/
https://ncbi.nlm.nih.gov/pubmed/28095320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.01.020
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