Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting

BACKGROUND: We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy. METHODS: In a randomized, double-blind, phase 3 trial, we compared olanzapine with placebo, in combination with dexamethasone, aprepitant or fosaprepitan...

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Udgivet i:N Engl J Med
Main Authors: Navari, Rudolph M., Qin, Rui, Ruddy, Kathryn J., Liu, Heshan, Powell, Steven F., Bajaj, Madhuri, Dietrich, Leah, Biggs, David, Lafky, Jacqueline M., Loprinzi, Charles L.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344450/
https://ncbi.nlm.nih.gov/pubmed/27410922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1515725
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