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β(3)-Adrenoceptor activation upregulates apolipoprotein A-I expression in HepG2 cells, which might further promote cholesterol efflux from macrophage foam cells
OBJECTIVE: The aim of this study was to explore the effects of β(3)-adrenoceptor (β(3)-AR) activation on HepG2 cells and its influence on cholesterol efflux from macrophage foam cells. MATERIALS AND METHODS: HepG2 cells were cultured and treated with the β(3)-AR agonist, BRL37344, and antagonist, SR...
Sparad:
I publikationen: | Drug Des Devel Ther |
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Huvudupphovsmän: | , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Dove Medical Press
2017
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344441/ https://ncbi.nlm.nih.gov/pubmed/28424539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S130088 |
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