Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome

BACKGROUND: Matrix metalloproteinase 8 (MMP-8) is the most potent type-I collagen protease. Such collagen mainly constitutes the transient fibrosis in takotsubo cardiomyopathy (TTC) endomyocardial biopsies. High MMP-8 and tissue-inhibitor of matrix metalloproteinase-1 (TIMP-1) levels are implicated...

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Vydáno v:PLoS One
Hlavní autoři: Parkkonen, Olavi, Nieminen, Mikko T., Vesterinen, Paula, Tervahartiala, Taina, Perola, Markus, Salomaa, Veikko, Jousilahti, Pekka, Sorsa, Timo, Pussinen, Pirkko J., Sinisalo, Juha
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344417/
https://ncbi.nlm.nih.gov/pubmed/28278213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173371
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