Decreased levels of irisin, a skeletal muscle cell-derived myokine, are related to emphysema associated with chronic obstructive pulmonary disease

BACKGROUND: Cigarette smoking-induced oxidant–antioxidant imbalance is a factor that contributes to the pathogenesis of COPD through epithelial cell apoptosis. Irisin is a skeletal muscle cell-derived myokine associated with physical activity. Irisin is also known to decrease oxidant-induced apoptos...

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Bibliographic Details
Published in:Int J Chron Obstruct Pulmon Dis
Main Authors: Sugiyama, Yukari, Asai, Kazuhisa, Yamada, Kazuhiro, Kureya, Yuko, Ijiri, Naoki, Watanabe, Tetsuya, Kanazawa, Hiroshi, Hirata, Kazuto
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344413/
https://ncbi.nlm.nih.gov/pubmed/28424548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S126233
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