The predictive and prognostic value of tumour necrosis in muscle invasive bladder cancer patients receiving radiotherapy with or without chemotherapy in the BC2001 trial (CRUK/01/004)

BACKGROUND: Severe chronic hypoxia is associated with tumour necrosis. In patients with muscle invasive bladder cancer (MIBC), necrosis is prognostic for survival following surgery or radiotherapy and predicts benefit from hypoxia modification of radiotherapy. Adding mitomycin C (MMC) and 5-fluorour...

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Библиографические подробности
Опубликовано в: :Br J Cancer
Главные авторы: Choudhury, Ananya, West, Catharine M, Porta, Nuria, Hall, Emma, Denley, Helen, Hendron, Carey, Lewis, Rebecca, Hussain, Syed A, Huddart, Robert, James, Nicholas
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
Предметы:
Molecular Diagnostics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344298/
https://ncbi.nlm.nih.gov/pubmed/28125821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.2
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