Aurora B expression modulates paclitaxel response in non-small cell lung cancer

BACKGROUND: Taxanes are mitotic poisons widely used in the treatment of non-small cell lung cancer (NSCLC), however, little is known about potential molecular modulators of response to these compounds. Aurora B (AURKB) is a critical regulator of the mitotic spindle assembly, previously shown overexp...

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Pubblicato in:Br J Cancer
Autori principali: Al-Khafaji, Ahmed SK, Davies, Michael PA, Risk, Janet M, Marcus, Michael W, Koffa, Maria, Gosney, John R, Shaw, Richard J, Field, John K, Liloglou, Triantafillos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344288/
https://ncbi.nlm.nih.gov/pubmed/28095398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.453
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