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Tumor-Associated Macrophages in Oncolytic Virotherapy: Friend or Foe?

Cancer therapy remains a challenge due to toxicity limitations of chemotherapy and radiation therapy. Oncolytic viruses that selectively replicate and destroy cancer cells are of increasing interest. In addition to direct cell lysis, these vectors stimulate an anti-tumor immune response. A key regul...

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Vydáno v:Biomedicines
Hlavní autoři: Denton, Nicholas L., Chen, Chun-Yu, Scott, Thomas R., Cripe, Timothy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344259/
https://ncbi.nlm.nih.gov/pubmed/28536380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines4030013
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