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Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4.

5-Lipoxygenase pathway-derived products of arachidonic acid released by human eosinophils activated in vitro have been measured by using radioimmunoassays specific for leukotriene B4 (LTB4) and for sulfidopeptide leukotrienes including leukotriene C4 (LTC4). Eosinophil-enriched leukocytes (mean, 85%...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Weller, P F, Lee, C W, Foster, D W, Corey, E J, Austen, K F, Lewis, R A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534393/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.24.7626
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