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Recognition of Local DNA Structures by p53 Protein

p53 plays critical roles in regulating cell cycle, apoptosis, senescence and metabolism and is commonly mutated in human cancer. These roles are achieved by interaction with other proteins, but particularly by interaction with DNA. As a transcription factor, p53 is well known to bind consensus targe...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Brázda, Václav, Coufal, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343910/
https://ncbi.nlm.nih.gov/pubmed/28208646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020375
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