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Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription.

We have studied somatic cell hybrids between mouse myeloma and JI Burkitt lymphoma cells carrying a t(2;8) chromosome translocation for the expression of human kappa chains. and for the presence and rearrangements of the human c-myc oncogene and kappa chain genes. Our results indicate that the c-myc...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Erikson, J, Nishikura, K, ar-Rushdi, A, Finan, J, Emanuel, B, Lenoir, G, Nowell, P C, Croce, C M
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1983
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6424112/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.24.7581
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