Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis

Manganese (Mn) is an important trace element present in human body, which acts as an enzyme co-factor or activator in various metabolic reactions. While essential in trace amounts, excess levels of Mn in human brain can produce neurotoxicity, including idiopathic Parkinson’s disease (PD)-like extrap...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Bahar, Entaz, Lee, Geum-Hwa, Bhattarai, Kashi Raj, Lee, Hwa-Young, Choi, Min-Kyung, Rashid, Harun-Or, Kim, Ji-Ye, Chae, Han-Jung, Yoon, Hyonok
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343836/
https://ncbi.nlm.nih.gov/pubmed/28146110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020300
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