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Oral Administration of Surface-Deacetylated Chitin Nanofibers and Chitosan Inhibit 5-Fluorouracil-Induced Intestinal Mucositis in Mice

This study investigated the prophylactic effects of orally administered surface-deacetylated chitin nanofibers (SDACNFs) and chitosan against 5-fluorouracil (5-FU)-induced intestinal mucositis, which is a common side effect of 5-FU chemotherapy. SDACNFs and chitosan abolished histological abnormalit...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Koizumi, Ryo, Azuma, Kazuo, Izawa, Hironori, Morimoto, Minoru, Ochi, Kosuke, Tsuka, Takeshi, Imagawa, Tomohiro, Osaki, Tomohiro, Ito, Norihiko, Okamoto, Yoshiharu, Saimoto, Hiroyuki, Ifuku, Shinsuke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343815/
https://ncbi.nlm.nih.gov/pubmed/28134832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020279
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