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HDAC Inhibitors and RECK Modulate Endoplasmic Reticulum Stress in Tumor Cells

In the tumor microenvironment hypoxia and nutrient deprived states can induce endoplasmic reticulum (ER) stress. If ER stress is not relieved, the tumor cells may become apoptotic. Therefore, targeting ER homeostasis is a potential strategy for cancer treatment. Various chemotherapeutic agents inclu...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Yun, Tsai, Ya-Hui, Tseng, Sheng-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343794/
https://ncbi.nlm.nih.gov/pubmed/28134767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020258
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