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ampC beta-lactamase hyperproduction in Escherichia coli: natural ampicillin resistance generated by horizontal chromosomal DNA transfer from Shigella.

Six ampicillin-resistant clinical isolates of Escherichia coli that hyperproduced the chromosomal ampC beta-lactamase were studied. By DNA sequence analysis, we found that five of them were identical over an entire 449-base-pair sequence and carried a novel strong ampC promoter [Olsson, O., Bergströ...

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Detalhes bibliográficos
Main Authors: Olsson, O, Bergström, S, Lindberg, F P, Normark, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534379/
https://ncbi.nlm.nih.gov/pubmed/6369321
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