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Influence of Transgenic Metallothionein-1 on Gliosis, CA1 Neuronal Loss, and Brain Metal Levels of the Tg2576 Mouse Model of Alzheimer’s Disease

The mouse model of Alzheimer’s disease (AD), Tg2576 mice (APP), has provided valuable information, such as the role of the metallothionein (MT) family in their behavioral and amyloidosis phenotypes. In this study, we further characterize the role of MT-1 by crossing Mt1-overexpressing mice with Tg25...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Comes, Gemma, Manso, Yasmina, Escrig, Anna, Fernandez-Gayol, Olaya, Sanchis, Paula, Molinero, Amalia, Giralt, Mercedes, Carrasco, Javier, Hidalgo, Juan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343787/
https://ncbi.nlm.nih.gov/pubmed/28134760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020251
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