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Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate.

The life span of neonatal rat cerebellar granule cells, grown in basal minimal Eagle's medium containing 10% (vol/vol) fetal calf serum, was extended to 21-30 days by weekly supplementation with glucose. Addition of 1% fetal calf serum to the culture at 14 days killed 85% of the cells within 1 hr. T...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schramm, M, Eimerl, S, Costa, E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.3.1193
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