Suppression of autophagy by mycophenolic acid contributes to inhibition of HCV replication in human hepatoma cells

Previous studies have shown that mycophenolic acid (MPA) has an anti-HCV activity. However, the mechanism of MPA-mediated inhibition of HCV replication remains to be determined. This study investigated whether MPA has an effect on autophagy, a cellular machinery required for HCV replication, thereby...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fang, Shoucai, Su, Jinming, Liang, Bingyu, Li, Xu, Li, Yu, Jiang, Junjun, Huang, Jiegang, Zhou, Bo, Ning, Chuanyi, Li, Jieliang, Ho, Wenzhe, Li, Yiping, Chen, Hui, Liang, Hao, Ye, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343675/
https://ncbi.nlm.nih.gov/pubmed/28276509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44039
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