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Multiple Faces of Dynamin-related Protein 1 and Its Role in Alzheimer’s Disease Pathogenesis

Mitochondria play a large role in neuronal function by constantly providing energy, particularly at synapses. Recent studies suggest that amyloid beta (Aβ) and phosphorylated tau interact with the mitochondrial fission protein, dynamin-related protein 1 (Drp1), causing excessive fragmentation of mit...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Kandimalla, Ramesh, Reddy, P. Hemachandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343673/
https://ncbi.nlm.nih.gov/pubmed/26708942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.12.018
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