The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein

The ability of the guanine-rich strand of the human mitochondrial DNA (mtDNA) to form G-quadruplex structures (G4s) has been recently highlighted, suggesting potential functions in mtDNA replication initiation and mtDNA stability. G4 structures in mtDNA raise the question of their recognition by fac...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Lyonnais, Sébastien, Tarrés-Soler, Aleix, Rubio-Cosials, Anna, Cuppari, Anna, Brito, Reicy, Jaumot, Joaquim, Gargallo, Raimundo, Vilaseca, Marta, Silva, Cristina, Granzhan, Anton, Teulade-Fichou, Marie-Paule, Eritja, Ramon, Solà, Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343656/
https://ncbi.nlm.nih.gov/pubmed/28276514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43992
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