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Tangier disease: defective recombination of a specific Tangier apolipoprotein A-I isoform (pro-apo A-i) with high density lipoproteins.

Isoforms of apolipoprotein A-I (apo A-I) from subjects with Tangier disease were characterized, and their ability to recombine with normal high density lipoproteins (HDL) was studied. In contrast to normal serum, in which isoprotein 4 is the dominant species [79 +/- 1.8% (mean +/- SD)], the Tangier...

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Main Authors: Schmitz, G, Assmann, G, Rall, S C, Mahley, R W
Formato: Artigo
Idioma:Inglês
Publicado: 1983
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC534364/
https://ncbi.nlm.nih.gov/pubmed/6412234
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