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The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells

The anti-diabetes drug metformin has been shown to have anti-neoplastic effects in several tumor models through its effects on energy metabolism and protein synthesis. Recent studies show that metformin also targets Hedgehog (Hh) signaling, a developmental pathway re-activated in several tumor types...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gonnissen, Annelies, Isebaert, Sofie, McKee, Chad M., Muschel, Ruth J., Haustermans, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343511/
https://ncbi.nlm.nih.gov/pubmed/28208838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020399
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