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Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.
The activation of specific T-cell clones by antigens is dependent upon the corecognition of restriction elements expressed on antigen-presenting cells (APC). For clones that respond by proliferation and lymphokine production, the restriction element is usually an Ia (I-region-associated) molecule. W...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1983
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534351/ https://ncbi.nlm.nih.gov/pubmed/6310611 |
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