Cerebrospinal Fluid Cortisol Mediates Brain-Derived Neurotrophic Factor Relationships to Mortality after Severe TBI: A Prospective Cohort Study

Distinct regulatory signaling mechanisms exist between cortisol and brain derived neurotrophic factor (BDNF) that may influence secondary injury cascades associated with traumatic brain injury (TBI) and predict outcome. We investigated concurrent CSF BDNF and cortisol relationships in 117 patients s...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Munoz, Miranda J., Kumar, Raj G., Oh, Byung-Mo, Conley, Yvette P., Wang, Zhensheng, Failla, Michelle D., Wagner, Amy K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343043/
https://ncbi.nlm.nih.gov/pubmed/28337122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00044
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