High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis

We have identified a population of T lymphocytes in peripheral blood, Vδ1 TCRγδ T lymphocytes, which unexpectedly was uniquely expressing high production of interferon-γ in newly diagnosed, untreated multiple sclerosis (MS) patients. IFN-γ production in this population distinctly correlated to param...

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Udgivet i:Front Immunol
Main Authors: Singh, Avadhesh Kumar, Novakova, Lenka, Axelsson, Markus, Malmeström, Clas, Zetterberg, Henrik, Lycke, Jan, Cardell, Susanna L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343019/
https://ncbi.nlm.nih.gov/pubmed/28337205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00260
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