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Productive infection of human neural progenitor cells by R5 tropic HIV-1: opiate co-exposure heightens infectivity and functional vulnerability

OBJECTIVE: HIV type-1 (HIV-1) causes a spectrum of central nervous system (CNS) complications; many are worsened by opiate co-exposure. Human neural progenitor cells (hNPCs) give rise to all CNS neurons and macroglia. We tested the hypothesis that hNPC maturation and fate are altered by HIV and opia...

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Detaylı Bibliyografya
Yayımlandı:AIDS
Asıl Yazarlar: Balinang, Joyce M., Masvekar, Ruturaj R., Hauser, Kurt F., Knapp, Pamela E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342937/
https://ncbi.nlm.nih.gov/pubmed/28099189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001398
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