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Epithelial-to-mesenchymal transition leads to disease-stage differences in circulating tumor cell detection and metastasis in pre-clinical models of prostate cancer

Metastasis is the cause of most prostate cancer (PCa) deaths and has been associated with circulating tumor cells (CTCs). The presence of ≥5 CTCs/7.5mL of blood is a poor prognosis indicator in metastatic PCa when assessed by the CellSearch(®) system, the “gold standard” clinical platform. However,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lowes, Lori E., Goodale, David, Xia, Ying, Postenka, Carl, Piaseczny, Matthew M., Paczkowski, Freeman, Allan, Alison L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342801/
https://ncbi.nlm.nih.gov/pubmed/27764810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12682
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