Overexpression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo

Lymphatic vessels function as transport channels for tumor cells to metastasize from the primary site into the lymph nodes. In this experiment we evaluated the effect of Sulfatase-1 (Sulf-1) on metastasis by upregulating it in murine hepatocarcinoma cell line Hca-F with high lymph node metastatic ra...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Mahmoud, Salma, Ibrahim, Mohammed, Hago, Ahmed, Huang, Yuhong, Wei, Yuanyi, Zhang, Jun, Zhang, Qingqing, Xiao, Yu, Wang, Jingwen, Adam, Munkaila, Guo, Yu, Wang, Li, Zhou, Shuting, Xin, Boyi, Xuan, Wei, Tang, Jianwu
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342722/
https://ncbi.nlm.nih.gov/pubmed/27626699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11933
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