Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells

Selective targeting of the PML/RARα oncoprotein demonstrates a successful molecular targeted therapy in acute promyelocytic leukemia (APL) with a typical t(15:17) chromosomal translocation. The zinc-thiolate coordination is critical for structural stability of zinc finger proteins, including the PML...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Misra, Sougat, Selvam, Arun Kumar, Wallenberg, Marita, Ambati, Aditya, Matolcsy, András, Magalhaes, Isabelle, Lauter, Gilbert, Björnstedt, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342695/
https://ncbi.nlm.nih.gov/pubmed/27732960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12531
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