Intravenous administration of xenogenic adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes markedly reduced brain infarct volume and preserved neurological function in rat after acute ischemic stroke

We tested the hypothesis that combined xenogenic (from mini-pig) adipose-derived mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy could reduce brain-infarct zone (BIZ) and enhance neurological recovery in rat after acute ischemic stroke (AIS) induced by 50-min left middle cerebral art...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Chen, Kuan-Hung, Chen, Chih-Hung, Wallace, Christopher Glenn, Yuen, Chun-Man, Kao, Gour-Shenq, Chen, Yi-Ling, Shao, Pei-Lin, Chen, Yung-Lung, Chai, Han-Tan, Lin, Kun-Chen, Liu, Chu-Feng, Chang, Hsueh-Wen, Lee, Mel S., Yip, Hon-Kan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper: Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342685/
https://ncbi.nlm.nih.gov/pubmed/27793019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12902
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