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Lowering serum lipids via PCSK9-targeting drugs: current advances and future perspectives
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as neural apoptosis regulated convertase (NARC1), is a key modulator of cholesterol metabolism. PCSK9 increases the serum concentration of low-density lipoprotein cholesterol by escorting low-density lipoprotein receptors (LDLRs) from...
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| Pubblicato in: | Acta Pharmacol Sin |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342665/ https://ncbi.nlm.nih.gov/pubmed/28112180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.134 |
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