In vitro assessment of the glucose-lowering effects of berberrubine-9-O-β-D-glucuronide, an active metabolite of berberrubine

Berberrubine (BRB) is the primary metabolite of berberine (BBR) that has shown a stronger glucose-lowering effect than BBR in vivo. On the other hand, BRB is quickly and extensively metabolized into berberrubine-9-O-β-D-glucuronide (BRBG) in rats after oral administration. In this study we compared...

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Publicado no:Acta Pharmacol Sin
Main Authors: Yang, Na, Sun, Run-bin, Chen, Xing-long, Zhen, Le, Ge, Chun, Zhao, Yu-qing, He, Jun, Geng, Jian-liang, Guo, Jia-hua, Yu, Xiao-yi, Fei, Fei, Feng, Si-qi, Zhu, Xuan-xuan, Wang, Hong-bo, Fu, Feng-hua, Aa, Ji-ye, Wang, Guang-ji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342660/
https://ncbi.nlm.nih.gov/pubmed/28042874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.120
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