Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca(2+) signaling in T24M-based bladder cancer models

Bladder cancer (BC) is the second most common malignancy of the genitourinary system, characterized by the highest recurrence rate of all cancers. Treatment options are limited; thus a thorough understanding of the underlying molecular mechanisms is needed to guide the discovery of novel therapeutic...

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Pubblicato in:Oncotarget
Autori principali: Frantzi, Maria, Klimou, Zoi, Makridakis, Manousos, Zoidakis, Jerome, Latosinska, Agnieszka, Borràs, Daniel M., Janssen, Bart, Giannopoulou, Ioanna, Lygirou, Vasiliki, Lazaris, Andreas C., Anagnou, Nicholas P., Mischak, Harald, Roubelakis, Maria G., Vlahou, Antonia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342587/
https://ncbi.nlm.nih.gov/pubmed/27683119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12218
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