Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates Epidermal Growth Factor Receptor in prostate cancer

Genomic loss of chromosome (chr) 8p21 region, containing prostate-specific NKX3.1 gene, is a frequent alteration of the prostate cancer (PCa) oncogenome. We propose a novel, paradigm shifting hypothesis that this frequently deleted locus is also associated with a cluster of microRNA genes- miR-3622a...

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Pubblicato in:Oncotarget
Autori principali: Bucay, Nathan, Sekhon, Kirandeep, Majid, Shahana, Yamamura, Soichiro, Shahryari, Varahram, Tabatabai, Z. Laura, Greene, Kirsten, Tanaka, Yuichiro, Dahiya, Rajvir, Deng, Guoren, Saini, Sharanjot
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342560/
https://ncbi.nlm.nih.gov/pubmed/27611943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11865
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