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iOri-Human: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition

The initiation of replication is an extremely important process in DNA life cycle. Given an uncharacterized DNA sequence, can we identify where its origin of replication (ORI) is located? It is no doubt a fundamental problem in genome analysis. Particularly, with the rapid development of genome sequ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhang, Chang-Jian, Tang, Hua, Li, Wen-Chao, Lin, Hao, Chen, Wei, Chou, Kuo-Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342515/
https://ncbi.nlm.nih.gov/pubmed/27626500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11975
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