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TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR-29b expression via activation of JNK-GATA3 signals

Vascular endothelial cell growth factor (VEGF) plays a pivotal role in promoting neovascularization. VEGF gene expression in vascular endothelial cells in normal tissues is maintained at low levels but becomes highly up-regulated in a variety of disease settings including cancers. Tumor necrosis fac...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Zhang, Kun, Cai, Hong-Xing, Gao, Shan, Yang, Gui-Li, Deng, Hui-Ting, Xu, Guo-Ce, Han, Jihong, Zhang, Qiang-Zhe, Li, Lu-Yuan
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342489/
https://ncbi.nlm.nih.gov/pubmed/27589684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11683
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