Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis

We retrospectively reviewed data from 123 patients (KIT exon 11 mutated) who received sunitinib or dose-escalated imatinib as second line. All patients progressed on imatinib (400 mg/die) and received a second line treatment with imatinib (800 mg/die) or sunitinib (50 mg/die 4 weeks on/2 off or 37.5...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Vincenzi, Bruno, Nannini, Margherita, Fumagalli, Elena, Bronte, Giuseppe, Frezza, Anna Maria, De Lisi, Delia, Ceruso, Mariella Spalato, Santini, Daniele, Badalamenti, Giuseppe, Pantaleo, Maria Abbondanza, Russo, Antonio, Tos, Angelo Paolo Dei, Casali, Paolo, Tonini, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342487/
https://ncbi.nlm.nih.gov/pubmed/26416414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.5136
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