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Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma

Genetic alterations of TERT and CTNNB1 have been documented in hepatocellular carcinoma. TERT promoter mutations are the earliest genetic events in the multistep process of hepatocarcinogenesis related to cirrhosis. However, analyses of TERT promoter and CTNNB1 mutations in hepatocellular carcinoma...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Seung Eun, Chang, Seong-Hwan, Kim, Wook Youn, Lim, So Dug, Kim, Wan Seop, Hwang, Tea Sook, Han, Hye Seung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342476/
https://ncbi.nlm.nih.gov/pubmed/27661004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12121
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